1. Therapeutic effects of bone marrow mesenchymal stem cells via modulation of TLR2 and TLR4 on renal ischemia-reperfusion injury in male Sprague-Dawley rats

Zeinab Karimi , Sahar Janfeshan, Elias Kargar Abarghouei, Seyedeh-Sara Hashemi*

BioImpacts. 2021;11(3): 219-226. doi: 10.34172/bi.2021.31

PMCID: PMC8314037 PMID: 34336610 Scopus ID: 85109076604

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Renal functional and structural disturbance induced by renal bilateral ischemia/reperfusion. However, administration of bone marrow stem cell (1.5×10⁶cells, i.p., per rat) improved renal function and appearance. Protective effect of BMSCs related to modulation of mRNA expression of TLR2 and TLR4.

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